🔬 Uses and Benefits

RABRIDEN DSR is primarily used to treat:

1. Gastroesophageal Reflux Disease (GERD): Manages symptoms like heartburn, chest pain, and regurgitation
2. Peptic Ulcer Disease: Helps heal ulcers in the stomach and duodenum
3. Acid Reflux: Reduces the backward flow of stomach acid into the esophagus
4. Indigestion: Relieves discomfort and pain associated with excess stomach acid
5. Nausea and Vomiting: The domperidone component helps control these symptoms

The combination provides comprehensive relief as it both reduces acid production and improves stomach emptying, making it more effective than either component alone for many patients with acid-related disorders.

📖 Instruction for Use

1. Take RABRIDEN DSR exactly as prescribed by your doctor
2. Take it on an empty stomach, preferably in the morning before breakfast
3. Swallow the capsule whole with a glass of water; do not crush, chew, or break it
4. The usual dosage is one capsule daily, but follow your doctor's specific instructions
5. Complete the full course of treatment even if symptoms improve before completion
6. Take the medication at the same time each day to maintain consistent levels in your body

⏱️ Forget/Missed Doses

If you miss a dose of RABRIDEN DSR:

• If remembered within 12 hours: Take the missed dose as soon as you remember
• If more than 12 hours have passed: Skip the missed dose and take your next dose at the regular time
• Do not double dose: Never take two doses to make up for a missed one

If you frequently forget doses, consider setting a daily alarm reminder or asking someone to help you remember.

🧬 How this Works

Rabeprazole (20mg):

• Acts as a proton pump inhibitor (PPI)
• Binds irreversibly to the H+/K+-ATPase enzyme system (the "proton pump") in gastric cells
• Blocks the final step of acid production, significantly reducing stomach acid levels
• Provides relief from acid-related symptoms and allows ulcers and damaged tissue to heal

Domperidone (30mg):

• Works as a dopamine receptor antagonist primarily in the peripheral nervous system
• Increases the motility and contractions of the stomach and upper intestines
• Promotes faster gastric emptying, preventing the backup of stomach contents
• Helps reduce nausea and vomiting through its action on the chemoreceptor trigger zone
• Improves overall digestive coordination

Together, these components address both the excessive acid production and the impaired stomach motility that often contribute to GERD and related conditions.

🛡️ Storage

To maintain the effectiveness of RABRIDEN DSR:

1. Store at room temperature (20°C to 25°C or 68°F to 77°F)
2. Keep the medication in its original container, tightly closed
3. Store in a dry place, away from moisture and direct sunlight
4. Keep out of reach of children and pets
5. Do not use the medication after the expiry date printed on the package
6. Do not store in the bathroom or other places with high humidity

⚠️ Side Effects

Common side effects may include:

• Headache
• Dizziness
• Diarrhea or constipation
• Stomach pain or discomfort
• Nausea
• Dry mouth
• Flatulence (gas)

Less common but more serious side effects (seek medical attention if experienced):

• Irregular heartbeat (higher risk in patients over 60 years)
• Severe allergic reactions (rash, itching, swelling, severe dizziness)
• Severe stomach pain
• Unusual tiredness or weakness
• Muscle spasms or tremors
• Signs of low magnesium (muscle cramps, irregular heartbeat)
• Signs of vitamin B12 deficiency (weakness, fatigue, numbness/tingling)

🔁 Over Doses

Symptoms of overdose may include:

• Severe drowsiness
• Confusion
• Severe headache
• Severe nausea or vomiting
• Rapid or irregular heartbeat
• Muscle spasms or movement disorders

In case of overdose, seek immediate medical attention or contact a poison control center.

💡 Safety Advice

Pregnancy and Breastfeeding:

• Not recommended during pregnancy unless clearly needed
• Avoid while breastfeeding as components may pass into breast milk

Alcohol:

• Avoid alcohol consumption while taking RABRIDEN DSR
• Alcohol can increase the risk of stomach damage and worsen side effects

Driving and Operating Machinery:

• May cause dizziness and drowsiness in some patients
• Avoid driving or operating machinery until you know how the medication affects you

Pre-existing Conditions:

• Inform your doctor if you have liver or kidney disease
• Use with caution in patients with heart conditions
• Not suitable for patients with certain gastrointestinal conditions like intestinal obstruction

Long-term Use:

• Prolonged use may lead to vitamin B12 and magnesium deficiency
• Regular monitoring for nutrient deficiencies may be necessary with extended use
• Follow up with your doctor for periodic assessment if using for more than 8 weeks

Special Precautions

1. Vitamin B12 Deficiency: Long-term use may lead to vitamin B12 deficiency, particularly in elderly patients
2. Magnesium Levels: Monitor for signs of hypomagnesemia with prolonged use
3. Heart Rhythm Issues: Use with caution in patients with heart conditions or those taking medications that affect heart rhythm
4. Bone Fractures: Long-term use may slightly increase risk of hip, wrist, or spine fractures
5. Kidney Function: Use with caution in patients with kidney problems
6. Liver Function: Dose adjustment may be needed in patients with severe liver disease

Remember to keep all follow-up appointments with your doctor to monitor your progress and address any potential side effects or complications.

By following these guidelines and consulting with your healthcare provider regularly, you can maximize the benefits of RABRIDEN DSR while minimizing potential risks.